Makindo Medical Notes"One small step for man, one large step for Makindo" |
|
---|---|
Download all this content in the Apps now Android App and Apple iPhone/Pad App | |
MEDICAL DISCLAIMER: The contents are under continuing development and improvements and despite all efforts may contain errors of omission or fact. This is not to be used for the assessment, diagnosis, or management of patients. It should not be regarded as medical advice by healthcare workers or laypeople. It is for educational purposes only. Please adhere to your local protocols. Use the BNF for drug information. If you are unwell please seek urgent healthcare advice. If you do not accept this then please do not use the website. Makindo Ltd. |
Related Subjects: |Thyrotoxicosis and Hyperthyroidism |Thyroid Storm - Thyrotoxic crisis |Graves Disease (Thyrotoxicosis) |Amiodarone and Thyroid disease |Thyroid Surgery (Thyroidectomy) |Hypothyroidism |Hashimoto's thyroiditis |DeQuervain's thyroiditis |Subacute Thyroiditis |Thyroid nodule |Congenital Hypothyroidism |Thyroid Function Tests and antibodies |Post partum thyroiditis |Sick Euthyroid Syndrome |Thyroid Exam (OSCE) |Thyroid Gland anatomy and Physiology |Thyroid Cancer
Clinical | TSH 0.2 - 4.0 miu/L | T3 | T4: 10 - 20 pmol/L |
---|---|---|---|
Primary Thyrotoxicosis | Undetectable | High | High |
Primary T3 Toxicosis | Undetectable | Normal | Raised |
Subclinical Thyrotoxicosis | Undetectable | Normal | Normal |
Non-thyroidal illness, Amiodarone | Low | High | Low/Normal |
Secondary hypothyroid | Normal | Low | Low |
Primary hypothyroid | Elevated | Low | Low |
Subclinical hypothyroid | Elevated | Normal | Normal |
Antibody | Target | Associated Condition(s) | Clinical Significance |
---|---|---|---|
Thyroid-Stimulating Immunoglobulin (TSI) | TSH Receptor | Graves' Disease | Stimulates TSH receptor, leading to hyperthyroidism and goiter. |
Thyrotropin Receptor Antibodies (TRAb) | TSH Receptor | Graves' Disease, Hashimoto's Thyroiditis | Can stimulate or block the TSH receptor, causing hyperthyroidism or hypothyroidism. |
Thyroid Peroxidase Antibody (TPO) | Thyroid Peroxidase | Hashimoto's Thyroiditis, Graves' Disease | Marker of autoimmune thyroid disease; indicates thyroid tissue destruction. |
Thyroglobulin Antibody (TgAb) | Thyroglobulin | Hashimoto's Thyroiditis, Graves' Disease | Associated with thyroid inflammation; affects thyroglobulin function. |
Blocking TSH Receptor Antibodies | TSH Receptor | Hypothyroid Graves', Neonatal Hypothyroidism | Blocks TSH receptor, preventing stimulation; causes hypothyroidism. |