Makindo Medical Notes"One small step for man, one large step for Makindo" |
|
---|---|
Download all this content in the Apps now Android App and Apple iPhone/Pad App | |
MEDICAL DISCLAIMER: The contents are under continuing development and improvements and despite all efforts may contain errors of omission or fact. This is not to be used for the assessment, diagnosis, or management of patients. It should not be regarded as medical advice by healthcare workers or laypeople. It is for educational purposes only. Please adhere to your local protocols. Use the BNF for drug information. If you are unwell please seek urgent healthcare advice. If you do not accept this then please do not use the website. Makindo Ltd. |
Related Subjects: |Analgesia |Sedation and Analgesia on ITU |Codeine |Dihydrocodeine |Diamorphine |Morphine
Opioid Drug | Dose | Comments: Provides analgesia and some sedation |
---|---|---|
Morphine | 1 mg/ml and give at 1-10 ml/hr in Normal saline | Familiar drug. Cheap and reliable. half life is long and so takes time to wear off. Onset can be slow up to 30 minutes |
Fentanyl | 50 mcg/ml and give at 1-10 ml/hr in Normal saline | Rapid onset. Can build up. |
Alfentanil | 500 mcg/ml and give at 1-10 ml/hr in Normal saline | Instant onset and rapid offset once stopped. |
Remifantanil | 100 mcg/ml and give at 1-10 ml/hr in Normal saline | Short acting. Expensive. Respiratory depressant |
Drug | Dose | Comments: Provides deep sedation |
---|---|---|
Propofol | Neat as 1% 10 mg/ml at 1-30 ml/hr or 2% 20 mg/ml at 1-20ml/hr | Can cause hypotension in large doses and respiratory depression. Rapid onset. can provide instant sedation of combative patients. Quick offset. Metabolic acidosis if prolonged use. Raised lipids and LFTs. |
Midazolam | 1 mg/ml at 1-20 ml/hr | Slow offset. Accumulates in renal failure |