• AIDS HIV Infection and a Fever ✅
  • Abacavir 💊
  • Abatacept 💊
  • Abciximab 💊
  • Abdominal Aortic Aneurysm (AAA) ✅
  • Abdominal Distension
  • Abdominal Masses: Clinical Approach and Considerations
  • Abnormal Involuntary Movements
  • Abnormal eating exercising behaviour (Children)
  • Abnormal urinalysis
  • Acamprosate 💊
  • Acarbose 💊
  • Acetazolamide 💊
  • Aciclovir 💊
  • Acoustic Neuroma ✅
  • Activated Charcoal
  • Actrapid (Insulin) 💊
  • Acute (Ascending) Cholangitis ✅
  • Acute Abdomen - Perforation of a Viscus
  • Acute Abdominal Pain - Children ✅
  • Acute Airway Obstruction
  • Acute Anaphylaxis ✅
  • Acute Appendicitis ✅
  • Acute Bacterial Meningitis (Adults) ✅
  • Acute Bronchitis ✅
  • Acute Change in Vision or Vision Loss (OSCE focused)
  • Acute Cholecystitis ✅
  • Acute Compartment Syndrome
  • Acute Coronary Syndrome (ACS): Chest Pain ❤️
  • Acute Coronary Syndrome: Overview
  • Acute Coronary Syndrome: Unstable Angina
  • Acute Delirium
  • Acute Encephalitis
  • Acute Epiglottitis
  • Acute Glaucoma
  • Acute Hepatitis and Acute Liver disease
  • Acute Hypotension ✅
  • Acute Kidney Injury ✅
  • Acute Limb Ischaemia
  • Acute Myocarditis ✅
  • Acute Pancreatitis ✅
  • Acute Pericarditis ✅
  • Acute Pyelonephritis and Urosepsis (UTI) ✅
  • Acute Renal / Ureteric Colic and Urinary Tract Stones ✅
  • Acute Respiratory Distress Syndrome (ARDS) ✅
  • Acute Severe Colitis
  • Acute Stroke Care Guidance UK Ireland 2023
  • Acute and Chronic Diarrhoea ✅
  • Acutely Ill Critical care patient with High NEWS
  • Adalimumab 💊
  • Adefovir 💊
  • Adenosine 💊
  • Adrenal crises (Paediatric) ✅
  • Adrenaline (Epinephrine) 💊
  • Adult Polycystic kidney disease ✅
  • Adverse Drug Effects
  • Age-Related Macular Degeneration (ARMD)
  • Alcohol Withdrawal (Delirium Tremens)
  • Alcoholic Hepatitis
  • Alendronate (Alendronic acid) 💊
  • Alfacalcidol 💊
  • Allergic disorders
  • Allergies
  • Allopurinol 💊
  • Alogliptin (Vipidia) 💊
  • Alteplase 💊
  • Aluminium and Magnesium Antacids
  • Alzheimer disease (Dementia) ✅
  • Amantadine 💊
  • Amenorrhoea
  • Amiloride
  • Aminoglycosides 💊
  • Aminophylline 💊
  • Aminosalicylates 💊
  • Amiodarone 💊
  • Amitriptyline 💊
  • Amlodipine 💊
  • Amoxicillin 💊
  • Amphotericin B 💊
  • Ampicillin 💊
  • Anaemia (Child Health)
  • Anaemia: Assessment ✅
  • Anagrelide 💊
  • Anakinra 💊
  • Anal Fissure
  • Andexanet alfa
  • Aneurysms, ischaemic limb and occlusions
  • Angiotensin Converting Enzyme Inhibitors
  • Angiotensin Converting enzyme (ACE) 💊
  • Anion Gap and Metabolic Acidosis
  • Ankylosing spondylitis
  • Anogenital Warts (HPV) ✅
  • Anosmia
  • Antacid medication
  • Anti-D immunoglobulin
  • Anti-OKT3 antibodies
  • Antiarrhythmic agents
  • Antibiotic Guidelines ✅
  • Antibiotics Mechanisms
  • Anticholinergic Burden
  • Anticoagulation and Antithrombotic
  • Antimicrobial Choices
  • Antimicrobial agents
  • Antimuscarinic drugs 💊
  • Anuria and Oliguria
  • Anxiety Phobias and OCD
  • Anxiety disorder: generalised (GAD)
  • Aortic Dissection ✅
  • Aortic Regurgitation ✅
  • Aortic Stenosis ✅
  • Apixaban 💊
  • Apomorphine 💊
  • Arrhythmias
  • Artemisinins 💊
  • Artesunate
  • Arthritis Diagnosis Compared
  • Asbestos Related Lung disease
  • Ascites ✅
  • Aspirin 💊
  • Assessing and Painful Red eye
  • Asthma COPD overlap syndrome
  • Asthma ✅
  • Atazanavir 💊
  • Atenolol 💊
  • Atorvastatin 💊
  • Atracurium
  • Atrial Fibrillation (AF) 💓 ✅
  • Atrial flutter 💓 ✅
  • Atropine Sulfate 💊
  • Attention deficit hyperactivity disorder
  • Auditory hallucinations
  • Azathioprine 💊
  • Azithromycin 💊
  • Back pain ✅
  • Baclofen 💊
  • Bacterial Vaginosis
  • Balsalazide (Aminosalicylate) 💊
  • Basal Cell Carcinoma (BCC) ✅
  • Beclometasone (Beclomethasone) 💊
  • Behaviour/personality change ✅
  • Behavioural and Psychological (BPSD) Symptoms of Dementia
  • Behavioural difficulties in Adults ✅
  • Behavioural difficulties in childhood
  • Bell's Palsy (Facial nerve palsy)
  • Bendroflumethiazide (Bendrofluazide) 💊
  • Benign Breast Disease
  • Benign Eyelid Conditions
  • Benign Paroxysmal Positional Vertigo (BPPV)
  • Benign Prostatic Hyperplasia ✅
  • Benzodiazepines
  • Benzylpenicillin Sodium (Penicillin G) 💊
  • Beriplex 💊
  • Beta Agonists 💊
  • Beta Antagonists/Blockers
  • Beta-lactamases 💊
  • Betahistine (Serc) 💊
  • Bezafibrate 💊
  • Bezafibrate 💊
  • Biliary atresia
  • Biological Agents
  • Bisacodyl 💊
  • Bisoprolol 💊
  • Bisphosphonates 💊
  • Bites and stings
  • Blackouts and faints (TLOC)
  • Bleeding Antepartum
  • Bleeding Postpartum
  • Bleomycin
  • Blindness - global causes
  • Blood Pressure
  • Blood Transfusion Reactions
  • Bone Pain
  • Bordetella pertussis (Whooping cough)
  • Brain Abscess
  • Brain Metastases
  • Breast Cancer ✅
  • Breast Cysts
  • Breast Lump Evaluation
  • Breast abscess and Mastitis and Fat Necrosis
  • Breast tenderness/pain
  • Breathlessness
  • Bretylium 💊
  • Bromocriptine 💊
  • Bronchiectasis
  • Bronchiolitis
  • Bruising
  • Budesonide 💊
  • Bumetanide
  • Buprenorphine 💊
  • Bupropion 💊
  • Burns Management Guide
  • Busulphan (Busulfan)
  • CNS fungal Infections
  • CNS infections
  • Cabergoline
  • Calcitonin
  • Calcitriol (1,25 Dihydroxycholecalciferol) 💊
  • Calcium Channel Blockers
  • Calcium Chloride or Gluconate
  • Calcium Resonium
  • Candesartan 💊
  • Candidiasis
  • Capecitabine 💊
  • Caplacizumab 💊
  • Capreomycin
  • Captopri 💊
  • Carbamazepine 💊
  • Carbimazole 💊
  • Cardiac Troponins
  • Cardiogenic shock
  • Cardiological Emergencies: Revision ✅
  • Cardiorespiratory Arrest
  • Caring for Patients with Dementia
  • Carmustine 💊
  • Carvedilol 💊
  • Cataract
  • Cauda Equina Syndrome (CES)
  • Causes of Limp in Children
  • Causes of Neck Pain/Stiffness
  • Causes of Stroke
  • Causes of a Limp in Adults
  • Causes of delayed Onset of Puberty in Children ✅
  • Cefaclor 💊
  • Cefalexin 💊
  • Cefotaxime 💊
  • Ceftazidime 💊
  • Ceftriaxone 💊
  • Cefuroxime 💊
  • Celecoxib 💊
  • Central Retinal Arterial Occlusion (CRAO)
  • Cerebral Palsy & HIE
  • Cervical Cancer screening
  • Cervical Smear Results ✅
  • Cervical cancer
  • Cervical screening (HPV)
  • Cetirizine 💊
  • Change in Bowel habit
  • Change in stool colour
  • Chemotherapeutic Agents
  • Chest Pain
  • Child abuse
  • Childhood Vaccination in the UK
  • Chlamydia Infections
  • Chlorambucil
  • Chloramphenicol 💊
  • Chlordiazepoxide 💊
  • Chloroquine 💊
  • Chlorphenamine(Chlorpheniramine) 💊
  • Chlorpromazine 💊
  • Chronic Fatigue Syndrome 🧠
  • Chronic Glaucoma
  • Chronic Kidney Disease (CKD) ✅
  • Chronic Obstructive Pulmonary Disease (COPD) ✅
  • Chronic Rash (Adult/Child)
  • Chronic abdominal pain
  • Chronic joint pain/stiffness 🦴
  • Ciclosporin 💊
  • Cimetidine 💊
  • Cinacalcet
  • Ciprofloxacin 💊
  • Cirrhosis
  • Cisplatin
  • Citalopram 💊
  • Cladribine
  • Clarithromycin 💊
  • Clindamycin 💊
  • Clinical Appearance Collections
  • Clonidine 💊
  • Clopidogrel 💊
  • Clotrimazole cream 💊
  • Clozapine 💊
  • Co Careldopa (Sinemet)
  • Co-Beneldopa (Madopar)
  • Co-codamol 💊
  • Co-trimoxazole (Trimethoprim + Sulfamethoxazole) 💊
  • CoAmoxiclav (Augmentin) 💊
  • Codeine 💊
  • Coeliac disease ✅
  • Colchicine 💊
  • Colorectal tumours ✅
  • Combined Oral contraceptive pill (COCP) 💊
  • Community Acquired Pneumonia 🫁 ✅
  • Comprehensive Geriatric Assessment (CGA)
  • Confusion (OSCE focused)
  • Congenital abnormalities
  • Conjunctivitis
  • Constipation (Adults) ✅
  • Contact Dermatitis
  • Contraception request/advice ✅
  • Cord Prolapse
  • Coronavirus SARS-CoV-2 (COVID-19) ✅
  • Corticosteroid-related psychosis 💊
  • Corticosteroids: Uses and Cautions
  • Cough (Adult)
  • Croup
  • Cryptogenic Organising Pneumonia (COP-BOOP)
  • Crystal arthropathy
  • Cushing syndrome
  • Cutaneous Warts
  • Cutaneous fungal infections
  • Cyclizine
  • Cyclo-oxygenase (COX) enzymes
  • Cyclophosphamide 💊
  • Cycloserine
  • Cys leukotriene receptor antagonists 💊
  • Cystic Fibrosis ✅
  • Dabigatran 💊
  • Dalteparin 💊
  • Dantrolene 💊
  • Dapagliflozin 💊
  • Darunavir 💊
  • Death and dying
  • Decreased appetite
  • Deep Vein Thrombosis (DVT) ✅
  • Dehydration (Child)
  • Dehydration Adult
  • Demeclocycline 💊
  • Dementias
  • Dengue Fever
  • Denosumab (Prolia) 💊
  • Dermatology Emergencies ✅
  • Desferrioxamine 💊
  • Desmopressin (DDAVP) 💊
  • Desogestrel (Progestogen Only Pill) 💊
  • Developmental Delay & Abnormal Development in Children
  • Dexamethasone 💊
  • Diabetes Insipidus (AVP Deficiency)
  • Diabetes Mellitus Type 1 ✅
  • Diabetes Mellitus Type 2 ✅
  • Diabetic Eye Disease
  • Diabetic Ketoacidosis (DKA) Adults ✅
  • Diabetic Ketoacidosis (DKA) Children
  • Diabetic nephropathy
  • Diabetic neuropathy
  • Diamorphine 💊
  • Diazepam 💊
  • Didanosine (ddI) 💊
  • Diethylstilbestrol
  • Difficulty with breastfeeding
  • Digoxin 💊
  • Dihydrocodeine 💊
  • Diltiazem 💊
  • Diplopia (Double Vision)
  • Dipyridamole 💊
  • Disease prevention/screening
  • Disopyramide 💊
  • Disseminated Intravascular Coagulation (DIC)
  • Disulfiram (Antabuse) 💊
  • Diuretics
  • Diverticular disease and Acute Diverticulitis ✅
  • Dizziness
  • Dobutamine 💊
  • Dog Bites ✅
  • Domperidone 💊
  • Donepezil (Aricept) 💊
  • Dopamine Hydrochloride 💊
  • Dopamine agonists 💊
  • Dosing Gentamicin
  • Downs syndrome
  • Doxapram 💊
  • Doxazosin (Cardura) 💊
  • Doxepin 💊
  • Doxorubicin (Adriamycin)
  • Doxycycline 💊
  • Driving Advice
  • Drug Metabolism
  • Drug Overdose Adults
  • Drug overdose children ✅
  • Drugs to Avoid in Acute Renal failure
  • Drugs to avoid in Liver failure
  • Dry and Wet and Gas Gangrene
  • Duchenne Muscular Dystrophy
  • Dulaglutide GLP-1 agonist 💊
  • Duloxetine 💊
  • Dysmorphic child
  • ECG - Acute Coronary Syndrome ❤️
  • ECG - Hyperkalaemia ❤️
  • ECG Reading & Interpretation MLA and Exams 🫀
  • ENT Emergencies: Revision ✅
  • ENT infections
  • Ear Pain (Otalgia)
  • Ear and Nasal Discharge
  • Eating Disorders
  • Ectopic Pregnancy
  • Eculizumab 💊
  • Eczema/Dermatitis
  • Edoxaban (Lixiana)
  • Efavirenz (Sustiva) EFV 💊
  • Elation/elated mood
  • Elder Abuse and Safeguarding
  • Electrolyte Abnormalities
  • Emtricitabine (Emtriva) FTC 💊
  • Enalapril 💊
  • Endocrine Emergencies: Revision ✅
  • Endometrial (Uterine) Cancer
  • Endometriosis
  • Enfuvirtide 💊
  • Enoxaparin Sodium (Clexane-Lovenox) 💊
  • Enoximone 💊
  • Entacapone
  • Enzyme inducers and inhibitors
  • Epididymitis and Orchitis (Children) ✅
  • Epididymitis and Orchitis in Adults
  • Epilepsy ✅
  • Epistaxis
  • Eplerenone 💊
  • Erectile dysfunction
  • Ergocalciferol (Calciferol) 💊
  • Erlotinib (Tarceva) 💊
  • Erythema Nodosum
  • Erythromycin 💊
  • Escitalopram 💊
  • Esomeprazole 💊
  • Essential Hypertension ✅
  • Essential Tremor
  • Etanercept 💊
  • Ethambutol 💊
  • Ethanol 💊
  • Etomidate
  • Etravirine (intelence) ETR 💊
  • Exenatide (Byetta) GLP1 agonist 💊
  • Extradural haemorrhage
  • Extrapyramidal symptoms
  • Eye Trauma
  • Eye pain/discomfort
  • Ezetimibe 💊
  • Facial and Periorbital Swelling
  • Facial pain
  • Faecal Incontinence
  • Falls
  • Family history of possible genetic disorder
  • Famotidine 💊
  • Fasciculation
  • Febrile convulsion
  • Felodipine (Dihydropyridine)
  • Fentanyl - Fentanil
  • Ferrous Fumarate - Gluconate - Sulphate 💊
  • Fever - all ages
  • Fibrotic Lung Disease
  • Fidaxomicin 💊
  • Finasteride (5 alpha-reductase inhibitor) 💊
  • First Seizure
  • Fit Notes in General Practice (UK)
  • Fixed Abnormal Beliefs (Delusions)
  • Flashes and Floaters in the Visual Field
  • Flecainide Acetate 💊
  • Flucloxacillin 💊
  • Fluconazole 💊
  • Flucytosine 💊
  • Fludrocortisone 💊
  • Flumazenil (Annexate - Romazicon) 💊
  • Fluoxetine 💊
  • Folate (Folic) acid (B9) 💊
  • Folinic acid (Leucovorin) 💊
  • Folliculitis
  • Fomepizole 💊
  • Fondaparinux 💊
  • Food Intolerance in Children
  • Foreign Body in Eye
  • Foscarnet Sodium 💊
  • Fosfomycin
  • Fosphenytoin 💊
  • Fractured Neck of Femur/Femoral Neck
  • Frailty an Overview
  • Full or Complete Blood Count (FBC CBC)
  • Furosemide (Frusemide)
  • Fusidic acid 💊
  • Gabapentin 💊
  • Galantamine
  • Gallstones and biliary colic
  • Ganciclovir - Valganciclovir 💊
  • Gas Gangrene (Clostridial Myonecrosis)
  • Gastric Cancer ✅
  • Gastroenteritis in Adults ✅
  • Gastroenteritis in Children
  • Gastrointestinal Emergencies: Revision ✅
  • General Basic Fracture management ✅
  • Genital Ulcers
  • Gentamicin 💊
  • Gestational Diabetes Mellitus ✅
  • Glatiramer acetate (Copaxone) 💊
  • Glibenclamide 💊
  • Gliclazide
  • Glimepiride
  • Glipizide
  • Glucagon 💊
  • Glyceryl Trinitrate (GTN) 💊
  • Glycopyrronium Bromide
  • Golimumab (Simponi) 💊
  • Gonorrhoea
  • Goserelin (Zoladex) 💊
  • Gradual change in or loss of vision
  • Griseofulvin 💊
  • Gynaecomastia ✅
  • Haematology Emergencies: Revision ✅
  • Haemoglobinopathies
  • Haemophilia A ✅
  • Haemoptysis
  • Haemorrhagic stroke
  • Haemorrhoids (Piles) ✅
  • Haloperidol 💊
  • Hartmanns solution (Ringers lactate) 💊
  • Head Injury and Traumatic Brain Head Injury (TBI)
  • Head Lice
  • Headaches
  • Heart Failure with preserved and reduced EF ✅
  • Heart Murmurs
  • Heparin - General 💊
  • Heparin - Low Molecular Weight Heparin 💊
  • Heparin - Unfractionated Heparin 💊
  • Hepatology Emergencies: Revision
  • Hereditary Haemochromatosis
  • Hernias (Children)
  • Herpes Simplex Virus
  • Herpes Varicella-Zoster (Shingles) Infection
  • Hiatus hernia
  • Hoarseness and voice change
  • Hodgkin vs Non-Hodgkin Lymphoma:
  • Hospital-acquired infections
  • Human albumin solution (HAS)
  • Human papilloma virus infection
  • Hydralazine 💊
  • Hydrocortisone 💊
  • Hydroxocobalamin - Cyanocobalamin (B12) 💊
  • Hydroxocobalamin 💊
  • Hydroxychloroquine 💊
  • Hyoscine (Buscopan) 💊
  • Hyperacute Stroke Care Pathway
  • Hypercalcaemia of Malignancy
  • Hypercalcaemia ✅
  • Hyperemesis Gravidarum
  • Hyperglycaemic Hyperosmolar State (HHS) ✅
  • Hyperkalaemia ✅
  • Hyperlipidaemia
  • Hyperparathyroidism
  • Hyperphosphataemia (High phosphate)
  • Hypertension in Children ✅
  • Hypertension in Pregnancy ✅
  • Hyperthermia and Hypothermia
  • Hypocalcaemia ✅
  • Hypoglycaemia
  • Hypokalaemia
  • Hypomagnesaemia ✅
  • Hyponatraemia ✅
  • Hypophosphataemia (Low phosphate)
  • Hypothyroidism ✅
  • Hypoxic-Ischaemic Encephalopathy
  • IV Immunoglobulin (IVIG) 💊
  • Ibandronic acid (Bisphosphonate) 💊
  • Ibuprofen 💊
  • Icatibant 💊
  • Idarucizumab (Praxbind) 💊
  • Idiopathic Arthritis in Adults
  • Imaging for the MLA#1
  • Imaging for the MLA#2
  • Imatinib mesylate
  • Imipenem (Primaxin) with Cilastin 💊
  • Immobility
  • Impetigo
  • Incidental Findings (Incidentalomas)
  • Indapamide 💊
  • Indinavir (IND)
  • Infant feeding issues
  • Infectious Colitis
  • Infectious Diarrhoea (OSCE focused)
  • Infectious Mononucleosis (EBV Most Often)
  • Infective Endocarditis
  • Infective Keratitis
  • Infertility & Subfertility
  • Inflammatory Bowel Disease
  • Infliximab 💊
  • Insulin Degludec (Tresiba)
  • Insulin Detemir (Levemir)
  • Insulin Glargine (Lantus, Abasaglar, Semglee, Toujeo)
  • Interferon Beta 💊
  • Intestinal Ischaemia
  • Intestinal obstruction and Ileus
  • Intrauterine death ✅
  • Intravenous Iron Replacement
  • Intussusception in Adults
  • Ipratropium Bromide (Atrovent) 💊
  • Irbesartan 💊
  • Iritis (Anterior Uveitis)
  • Iron Salts 💊
  • Irritable bowel syndrome ✅
  • Isoniazid 💊
  • Isoprenaline 💊
  • Isosorbide Dinitrate 💊
  • Isosorbide mononitrate 💊
  • Isotretinoin (Accutane) 💊
  • Ispaghula Husk (Fybogel) 💊
  • Ivabradine 💊
  • Jaundice
  • Kawasaki disease
  • Ketamine 💊
  • Ketoconazole 💊
  • L-Thyroxine (T4) 💊
  • Labetalol (Trandate) 💊
  • Labour and Complications
  • Lacerations
  • Lactulose 💊
  • Lacunar Stroke Syndromes
  • Lamivudine (3TC) 💊
  • Lamotrigine 💊
  • Lansoprazole 💊
  • Lanthanum
  • Large for Gestational Age (LGA)
  • Laxatives 💊
  • Learning (Intellectual) disability
  • Leflunomide (Arava) 💊
  • Lenalidomide (Revlimid)
  • Leukaemia
  • Levetiracetam (Keppra) 💊
  • Levodopa 💊
  • Levomepromazine
  • Levosimendan 💊
  • Lidocaine(Lignocaine) 💊
  • Limb Weakness
  • Linagliptin (Trajenta) 💊
  • Linezolid
  • Liothyronine Sodium L-Triiodothyronine (T3) 💊
  • Lipid emulsion therapy - Intralipid 💊
  • Liraglutide (Victoza) 💊
  • Lisinopril 💊
  • Lithium 💊
  • Lofepramine 💊
  • Loin Pain
  • Loop diuretics 💊
  • Loperamide 💊
  • Lopinavir 💊
  • Loratadine 💊
  • Lorazepam 💊
  • Losartan 💊
  • Loss of Libido
  • Loss of red reflex
  • Low mood/affective/depression problems
  • Lower Gastrointestinal Bleeding ✅
  • Lower Limb Fractures
  • Lower Limb Soft Tissue Injuries
  • Lower respiratory tract infection (Child)
  • Lugol iodine 💊
  • Lump in Groin
  • Lung Cancer
  • Lyme disease
  • Lymphadenopathy
  • Magnesium Physiology
  • Magnesium Sulphate - Sulfate
  • Malaria
  • Malignant Breast Disease
  • Malignant Hyperpyrexia (Malignant Hyperthermia)
  • Malignant Hypertension
  • Malignant Melanoma ✅
  • Malnutrition Adults and the Elderly
  • Malnutrition in Children 🍽️
  • Mannitol
  • Maraviroc (Celsentri) 💊
  • Massive Haemorrhage and Massive Transfusion Protocol (MTP)
  • Measles (notifiable)
  • Mebeverine 💊
  • Mefenamic acid 💊
  • Mefloquine (Larium)
  • Melaena
  • Melatonin
  • Memantine Hydrochloride 💊
  • Memory Loss
  • Menieres disease
  • Menopause and Menopausal Problems 🌸 ✅
  • Menstrual problems
  • Mental capacity concerns
  • Mental health problems in pregnancy or postpartum 🤰
  • Mercaptopurine 💊
  • Meropenem 💊
  • Mesalazine (Aminosalicylate) 💊
  • Mesenteric adenitis
  • Metabolic acidosis
  • Metabolic alkalosis
  • Metastatic disease
  • Metformin 💊
  • Methodone 💊
  • Methotrexate 💊
  • Methylcellulose 💊
  • Methylprednisolone
  • Metoclopramide 💊
  • Metolazone 💊
  • Metoprolol 💊
  • Metronidazole (Flagyl) 💊
  • Metyrapone (Metopirone) 💊
  • Miconazole 💊
  • Midazolam
  • Midodrine 💊
  • Migraine ✅
  • Milrinone
  • Minocycline 💊
  • Minoxidil 💊
  • Mirabegron 💊
  • Mirtazapine 💊
  • Miscarriage
  • Misoprostol 💊
  • Misplaced Nasogastric tube insertion
  • Mitral Regurgitation (Incompetence)
  • Mitral Stenosis ✅
  • Montelukast 💊
  • Morphine Sulphate 💊
  • Motor Neuron Disease (MND-ALS)
  • Multiple Myeloma
  • Multiple Organ Dysfunction Syndrome
  • Multiple Sclerosis (MS)
  • Mumps (Notifiable)
  • Muscle Pain Myalgia
  • Muscular Dystrophies
  • Musculoskeletal deformities
  • Musculoskeletal deformities
  • Myasthenia Gravis
  • Mycophenolate mofetil 💊
  • Myeloproliferative disorders ✅
  • N-Acetylcysteine (Parvolex) 💊
  • Naloxone (Narcan) Opiate antagonist 💊
  • Naproxen
  • Nasal Discharge
  • Natalizumab (Tysabri) 💊
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  • Download the amazing global Makindo app: ✅ Means NICE/National Guidelines 2026 compliant Android | Apple
    MEDICAL DISCLAIMER: Educational use only. Not for diagnosis or management. See below for full disclaimer.

    Haemorrhoids (Piles) ✅

    🩸 Key sign: Haemorrhoidal bleeding is typically bright red, often seen on toilet paper, on the outside of the stool, or dripping into the pan. Pain is not typical of uncomplicated internal haemorrhoids; marked pain suggests thrombosis, prolapse/strangulation, fissure, abscess, or another diagnosis.

    📖 About
    • Haemorrhoids are normal vascular cushions in the anal canal; they help contribute to continence.
    • Symptoms occur when these cushions become enlarged, bleed, prolapse, thrombose, or become inflamed.
    • Internal haemorrhoids arise above the dentate line and are usually painless unless prolapsed/strangulated.
    • External haemorrhoids arise below the dentate line and can be painful, especially if thrombosed.
    ⚠️ Risk Factors
    • Constipation, straining, hard stools, prolonged time on the toilet.
    • Low-fibre diet and inadequate fluid intake.
    • Pregnancy and other causes of raised intra-abdominal pressure.
    • Increasing age and weakening of supporting connective tissue.
    🩺 Clinical Features
    • Bright-red rectal bleeding, usually not mixed with stool.
    • Anal swelling or prolapse during/after defaecation.
    • Pruritus, mucus soiling, irritation, or a sensation of incomplete cleaning.
    • Severe pain suggests thrombosed external haemorrhoid or another anorectal pathology rather than simple internal piles.
    📊 Classification of internal haemorrhoids
    • Grade I: bleed but do not prolapse.
    • Grade II: prolapse with defaecation but reduce spontaneously.
    • Grade III: prolapse and require manual reduction.
    • Grade IV: irreducibly prolapsed.
    🔍 Assessment
    • Take a careful history of bleeding pattern, bowel habit, pain, weight loss, anaemia symptoms, family history, and colorectal cancer risk factors.
    • Examine the perianal area and perform digital rectal examination if appropriate.
    • Consider proctoscopy/anoscopy to confirm internal haemorrhoids if the diagnosis is uncertain or symptoms persist.
    • Routine FBC/U&E/CRP are not needed for straightforward haemorrhoids; investigate further only if the history suggests anaemia, significant bleeding, infection, systemic illness, or an alternative diagnosis.
    🚩 Red flags / when not to assume piles
    • Persistent rectal bleeding, especially in older adults.
    • Iron-deficiency anaemia.
    • Change in bowel habit, weight loss, abdominal pain, or tenesmus.
    • Palpable rectal or abdominal mass.
    • Systemic symptoms or diagnostic uncertainty.
    📌 NICE referral points
    • Refer on a suspected cancer pathway for adults with a rectal mass.
    • Refer on a suspected cancer pathway for adults aged 50 and over with unexplained rectal bleeding.
    • Consider urgent referral for adults aged under 50 with rectal bleeding plus abdominal pain, change in bowel habit, weight loss, or iron-deficiency anaemia.
    • For people without rectal bleeding but with unexplained lower GI symptoms who do not meet immediate referral criteria, NICE supports use of FIT to help guide colorectal cancer pathway referral.
    💊 Management
    • Conservative first-line: increase dietary fibre, fluids, avoid straining, treat constipation, and encourage good toilet habits.
    • Use bulk-forming laxatives or stool-softening measures if needed to keep stools soft and easy to pass.
    • Topical preparations may help short-term symptoms, but evidence is limited and they do not treat the underlying cause.
    • Topical corticosteroid-containing products should be used only occasionally and short term (generally no more than 7 days).
    🩹 Procedures
    • Rubber band ligation (RBL): common office treatment for symptomatic grade I–II internal haemorrhoids, and selected grade III cases.
    • Injection sclerotherapy: another outpatient option, especially for lower-grade bleeding haemorrhoids.
    • Haemorrhoidal artery ligation / HALO: may be considered in selected patients.
    • Haemorrhoidectomy: usually reserved for grade IV, mixed internal/external disease, or symptoms refractory to outpatient procedures.
    🚑 Thrombosed external haemorrhoid
    • Typically presents with sudden severe anal pain and a tender bluish perianal lump.
    • Initial treatment is usually analgesia, stool-softening measures, and local care.
    • If presentation is very early (for example within 72 hours) and pain is severe, urgent specialist assessment may be appropriate because excision can sometimes be considered.
    ⚠️ Complications
    • Thrombosis.
    • Prolapse and strangulation.
    • Mucus leakage, irritation, and skin tags.
    • Anaemia is possible with ongoing bleeding but is not typical of simple haemorrhoids and should prompt broader assessment.
    🔄 Differentials
    • Anal fissure.
    • Perianal abscess or fistula.
    • Rectal prolapse.
    • Colorectal cancer or large polyps.
    • Inflammatory bowel disease, proctitis, or infectious anorectal disease.

    🌟 Teaching pearl: Painless bright-red bleeding suggests internal haemorrhoids, but rectal bleeding should never be dismissed without considering colorectal cancer. Pain points you away from simple internal piles and toward thrombosis, fissure, strangulation, or sepsis.

    📚 References
    Clinical Cases
    • 🩸 Case 1 – Age 28: Painless bright-red bleeding on wiping, no weight loss, no altered bowel habit, no anaemia symptoms. Examination suggests small grade I internal haemorrhoids. Management: Fibre, fluids, bowel habit advice, short-term symptomatic treatment only. Teaching point: In younger low-risk patients with typical symptoms, conservative treatment is appropriate, but safety-net if bleeding persists.
    • 💢 Case 2 – Age 46: Prolapsing tissue on defaecation requiring manual reduction, intermittent bleeding, no red-flag features. Management: Grade III internal haemorrhoids; discuss outpatient procedural treatment such as banding, while continuing bowel habit optimisation. Teaching point: Prolapse severity guides intervention more than bleeding alone.
    • 🚑 Case 3 – Age 62: Severe pain with a tender bluish perianal lump. Management: Likely thrombosed external haemorrhoid; give analgesia and stool-softening advice, and consider urgent specialist review if onset is recent and pain is severe. Teaching point: Painful perianal swelling is not the classic presentation of internal piles.

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