Makindo Medical Notes"One small step for man, one large step for Makindo" |
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Infection Type | Clinical Information | Clinical Tests | Management |
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Chlamydia Trachomatis (Genital Infection) |
- The most common sexually transmitted infection (STI) caused by Chlamydia trachomatis.
- Often asymptomatic but can present with dysuria, abnormal genital discharge, pelvic pain, or post-coital bleeding. - Can lead to complications such as pelvic inflammatory disease (PID) in women and epididymitis in men. |
- Nucleic Acid Amplification Test (NAAT) on urine (men) or vaginal/cervical swabs (women).
- NAAT testing of rectal and pharyngeal swabs in cases of receptive anal or oral intercourse. - Urine sample for men, self-taken vaginal swab for women. |
- First-line: Doxycycline 100 mg twice daily for 7 days.
- Alternative: Single dose of Azithromycin 1g. - Partner notification and treatment. - Abstain from sexual activity until treatment is complete. - Retest in 3 months for reinfection. |
Chlamydia Pneumoniae (Respiratory Infection) |
- Chlamydia pneumoniae can cause respiratory tract infections, including pneumonia, bronchitis, and sinusitis.
- Symptoms may include cough, sore throat, fever, and fatigue. - May lead to atypical pneumonia, especially in elderly or immunocompromised patients. |
- PCR or serology for Chlamydia pneumoniae antibodies.
- Chest X-ray to assess for pneumonia. - Sputum culture (less commonly used for diagnosis). |
- Doxycycline or azithromycin as first-line treatment.
- Clarithromycin or levofloxacin as alternatives. - Symptomatic care (e.g., fever management, hydration). - Follow-up chest X-ray if pneumonia is diagnosed. |
Chlamydia Conjunctivitis (Adult Inclusion Conjunctivitis) |
- Caused by Chlamydia trachomatis, often associated with genital infection.
- Symptoms include unilateral red eye, mucopurulent discharge, and irritation. - May be linked to sexual transmission or autoinoculation from genital secretions. |
- NAAT testing on conjunctival swabs.
- PCR test to confirm infection. - Slit-lamp exam for assessing ocular inflammation. |
- Oral doxycycline or azithromycin for 7-14 days.
- Topical antibiotic eye drops (e.g., erythromycin) as adjunctive therapy. - Sexual partner treatment to prevent reinfection. - Avoid contact lens use during treatment. |
Lymphogranuloma Venereum (LGV) |
- An invasive infection caused by certain strains of Chlamydia trachomatis, primarily affecting lymphatic tissue.
- Initially presents with a small painless genital ulcer or papule, followed by painful swollen lymph nodes (buboes). - Rectal LGV can cause proctitis, rectal pain, and discharge. |
- NAAT testing on genital, rectal, or pharyngeal swabs.
- PCR for LGV-specific strains. - Biopsy of lymph nodes in cases of buboes. |
- Doxycycline 100 mg twice daily for 21 days.
- Azithromycin as an alternative. - Drainage of buboes if necessary. - Partner notification and treatment. - Screening for other STIs. |