Makindo Medical Notes"One small step for man, one large step for Makindo" |
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Related Subjects: |Atrial Fibrillation |Sinus Tachycardia |Sinus Arrhythmia |Multifocal Atrial Tachycardia |Resuscitation - Adult Tachycardia Algorithm
Smokers need higher dose; elderly or CCF smaller dose. Ensure correct brand is used as there are different formulations with different bioavailability. Complex interactions. Always check with existing drugs.
Name | Starting Dose | Frequency | Route |
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Aminophylline Oral | 225-450 mg BD for non-smokers | OD | PO |
Aminophylline Oral | 350-700 mg BD for smokers | BD | PO |
Aminophylline loading dose IVl | 5 mg/kg (250-500 mg) if not on drug already | Once | IV over 1 hour |
Aminophylline Maintenance dose IV | 500-750 mg over 24 hrs Aim for serum levels of 10-20 mg/L Wait until 4-6 h after infusion started. Stop infusion and wait 15 min and then take level. | Infusion | IV over 4 hr |