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Related Subjects: |Calcium Physiology |Hypercalcaemia |Bisphosphonates |Osteoporosis |Osteonecrosis of the jaw
Cancer patients need a dental check before treatment, or as soon as possible after starting treatment, to avoid osteonecrosis of the jaw.
Atypical femoral fractures have been reported rarely with bisphosphonate treatment, mainly in patients receiving long-term treatment for osteoporosis. The need to continue bisphosphonate treatment for osteoporosis should be re-evaluated periodically based on an assessment of the benefits and risks of treatment for individual patients, particularly after 5 or more years of use. Patients should be advised to report any thigh, hip, or groin pain during treatment with a bisphosphonate. Discontinuation of bisphosphonate treatment in patients suspected to have an atypical femoral fracture should be considered after an assessment of the benefits and risks of continued treatment.