Atrial flutter ๐ โ
Related Subjects:
|Wolff-Parkinson White syndrome (WPW) AVRT
|Lown Ganong Levine Syndrome AVRT
|Supraventricular Tachycardia (SVT)
|Atrioventricular Nodal Reentrant Tachycardia AVNRT
|Atrial Flutter
|Atrial Fibrillation
|Sinus Tachycardia
|Sinus Arrhythmia
|Multifocal Atrial Tachycardia
|Resuscitation - Adult Tachycardia Algorithm
|AF and Anticoagulation
โ ๏ธ Important: Class I antiarrhythmics (e.g. flecainide) must be used with AV nodal blockade (ฮฒ-blocker or rate-limiting calcium channel blocker) to prevent dangerous 1:1 AV conduction โก.
โ Avoid antiarrhythmic monotherapy in atrial flutter.
๐ฅ Catheter ablation (targeting the re-entrant circuit) has >90% success and is first-line definitive therapy in typical flutter.
โน๏ธ About Atrial Flutter
- โก Atrial rate: 280โ350 bpm due to a macro-reentrant circuit.
- ๐ง Ventricular rate typically ~150 bpm with 2:1 AV block.
- ๐ Often alternates with atrial fibrillation (AFโflutter spectrum).
- ๐ Usually originates in the right atrium (cavotricuspid isthmus-dependent circuit).
๐งฌ Aetiology
- ๐ Macro-reentrant arrhythmia (classically cavotricuspid isthmus dependent).
- โค๏ธ Structural heart disease: IHD, hypertension, valvular disease, cardiomyopathy.
- ๐ฌ๏ธ Systemic triggers: COPD, hyperthyroidism, infection, alcohol (โholiday heartโ ๐ท).
- ๐ ๏ธ Post-cardiac surgery or prior ablation โ atypical flutter.
๐ Types of Atrial Flutter
| Type |
Characteristics |
Clinical Notes |
| Typical (CTI-dependent) |
Re-entry around tricuspid annulus via cavotricuspid isthmus |
Most common; highly amenable to catheter ablation ๐ฅ |
| Atypical |
Nonโisthmus dependent circuits (often scar-related) |
Seen post-surgery/ablation; requires complex mapping |
๐ ECG Findings
- ๐ช Sawtooth flutter waves, best seen in leads II, III, aVF.
- โก 2:1 AV conduction โ ventricular rate ~150 bpm (common).
- ๐จ 1:1 conduction โ ventricular rate 250โ300 bpm (life-threatening).
- ๐ Adenosine or vagal manoeuvres may unmask flutter waves.
๐ค Clinical Presentation
- ๐ Palpitations, fatigue, dyspnoea, dizziness.
- ๐ง May be asymptomatic if rate controlled.
- ๐จ Severe cases: hypotension, syncope, acute heart failure.
๐ฌ Investigations
- ๐งช Bloods: FBC, U&E, Mgยฒโบ, TFTs, CRP, troponin.
- ๐ ECG: diagnostic (flutter waves + conduction pattern).
- ๐ฉป Echocardiography: assess LV function, atrial size, valvular disease.
- ๐ Holter monitor: paroxysmal detection.
- ๐ Adenosine: diagnostic (transient AV block reveals flutter waves).
โก Acute Management (NICE NG196)
- ๐จ Haemodynamically unstable: Immediate synchronized DC cardioversion.
- ๐ง Stable: Rate control first-line (ฮฒ-blocker or rate-limiting CCB).
- โฑ๏ธ Consider early cardioversion if onset <48h or patient anticoagulated.
๐๏ธ Rate Control
- ฮฒ-blockers (e.g. bisoprolol) ๐
- Rate-limiting CCBs (diltiazem/verapamil) ๐
- Digoxin useful in sedentary patients or heart failure โ ๏ธ (less effective in exertion)
๐ Rhythm Control
- โก Electrical cardioversion โ rapid and effective.
- ๐ Flecainide (ONLY if no structural heart disease) + AV nodal blocker.
- ๐ Amiodarone reserved for structural heart disease or refractory cases.
๐ฅ Catheter Ablation
- ๐ฏ First-line definitive therapy for typical atrial flutter.
- ๐ Success rate >90%; low recurrence.
- Reduces need for long-term antiarrhythmic drugs.
๐ก๏ธ Anticoagulation (NICE NG196)
- ๐ Use CHAโDSโ-VASc score (same as AF).
- ๐ DOACs first-line (apixaban, rivaroxaban, dabigatran, edoxaban).
- โ๏ธ Warfarin if mechanical valve or moderateโsevere mitral stenosis.
- โ Do NOT use aspirin monotherapy for stroke prevention.
๐ซ Contraindications / Caution
- โ Flecainide in structural heart disease or IHD.
- โ Non-DHP CCBs in decompensated systolic heart failure.
- โ ๏ธ Excess ฮฒ-blockade โ bradycardia, hypotension.
- โ ๏ธ Antiarrhythmics without AV nodal blockade โ risk of 1:1 conduction โก
๐ Rate vs Rhythm Control
| Scenario |
Preferred Strategy |
Rationale |
| ๐จ Unstable |
Immediate DC cardioversion |
Life-saving; do not delay |
| ๐ท Symptomatic stable |
Rate control โ consider rhythm control |
Stabilise first, then restore sinus rhythm |
| ๐ Recurrent flutter |
Catheter ablation |
Definitive, high success |
| ๐ด Older/comorbid |
Rate control + anticoagulation |
Avoid drug toxicity; stroke prevention key |
๐ฉบ Case-Based Learning
- Case 1: 66M, HR 150 โ typical flutter.
โ ฮฒ-blocker โ consider cardioversion โ ablation. ๐ง
- Case 2: 78F, HF + flutter.
โ Digoxin + diuretics โ anticoagulate โ consider ablation. โค๏ธ
- Case 3: 70M, HR 280, hypotensive.
โ ๐จ Immediate DC cardioversion. โก
๐ฑ Lifestyle & Risk Factor Management
- ๐ญ Smoking cessation
- ๐ท Reduce alcohol intake
- โ๏ธ Weight optimisation
- ๐ Treat HTN, thyroid disease, COPD
๐ References