Makindo Medical Notes

Related Subjects: | Transverse myelitis | Acute Disseminated Encephalomyelitis |Cervical spondylosis |Spinal Cord Anatomy |Acute Disc Prolapse |Spinal Cord Compression |Spinal Cord Haematoma |Foix-Alajouanine syndrome |Cauda Equina |Conus Medullaris syndrome |Anterior Spinal Cord syndrome |Central Spinal Cord syndrome |Brown-Sequard Spinal Cord syndrome

Difficult cases include head injury and coma with a coexisting neck injury. In any doubt, apply a hard collar to stabilize the neck. If the head is scanned in such cases, obtain cervical spine films up to the C7/T1 level to ensure no spinal injury is missed.

About

• Early management of spinal injuries is crucial as delays can lead to long-term neurological consequences.
• The spinal cord extends from the foramen magnum (base of the skull) to the L1 vertebra, controlling motor and sensory functions throughout the body.
• Segments C3-5 supply the diaphragm, essential for breathing.
• Segments C5-T1 supply motor and sensory functions to the arms and hands.

Anatomy

• The human spine consists of 31 pairs of spinal nerves, categorized as follows:
  • Cervical: 8 pairs (C1 through C8)
  • Thoracic: 12 pairs (T1 through T12)
  • Lumbar: 5 pairs (L1 through L5)
  • Sacral: 5 pairs (S1 through S5)
  • Coccygeal: 1 pair (Co1)

Aetiology

• Traumatic Causes:
  • Anterior Dislocation of a Vertebra: Trauma can cause the vertebra to dislocate anteriorly, potentially transecting the spinal cord.
  • Fracture-Dislocation: Severe trauma can lead to fractures and dislocations, seen in both young and elderly populations.
  • Bone Fragment Impingement: Fragments from fractured vertebrae can press against the spinal cord, causing damage.
  • Hematoma Formation: Bleeding within the spinal canal can lead to ischemic damage of the spinal cord.
• Non-Traumatic Causes:
  • Infections such as meningitis or epidural abscesses.
  • Tumors compressing the spinal cord.
  • Degenerative diseases like cervical spondylosis leading to spinal canal narrowing.

Structure

• The spinal column is divided into three columns:
  • Anterior Column: Comprises the anterior half of the vertebral body and associated ligaments.
  • Middle Column: Includes the posterior longitudinal ligament and the posterior half of the vertebral body.
  • Posterior Column: Consists of the laminae, pedicles, and associated ligaments.
• Damage to any two out of the three columns indicates an unstable spine, necessitating surgical intervention to prevent further injury.

Causes

• Road Traffic Accidents: Account for approximately 50% of spinal injuries, especially when individuals are ejected from vehicles.
• Falls: Responsible for about 25% of cases, particularly in the elderly who may fall from standing height or greater.
• Violence: Includes gunshot wounds and stab injuries, making up around 15% of spinal injuries.
• Sports Accidents: Contribute to about 10% of spinal injuries, common in activities like diving, rugby, and other high-impact sports.
• Other Causes: Account for the remaining 5%, including industrial accidents, heavy lifting, and other miscellaneous traumas.

Risk Factors

• Ankylosing Spondylitis: Chronic inflammatory disease causing spinal fusion and increasing injury risk.
• Cervical Spondylosis: Degenerative changes in the cervical spine leading to spinal canal narrowing.
• Narrow Spinal Canal: Congenital or acquired conditions that reduce the space available for the spinal cord.

Dangerous Mechanisms

• Falls from elevation of three feet or more (e.g., five steps).
• Axial load to the head, such as diving into shallow water.
• High-speed motor vehicle collisions, especially rollover accidents or ejection from the vehicle.
• Accidents involving motorized recreational vehicles like ATVs or motorcycles.
• Bicycle collisions with vehicles.
• Rear-end collisions resulting in being pushed into traffic or hit by larger vehicles like buses or trucks.

Clinical Features

• Spinal Shock: Acute phase characterized by loss of reflexes below the lesion, flaccid limbs, atonic bladder, and loss of vasomotor control. This phase can last up to two weeks.
• Heightened Neuroreflexes: Occur after spinal shock resolves, leading to spasticity of limbs, increased reflexes, upgoing plantar responses (Babinski sign), spastic bladder, and heightened autonomic functions like sweating.
• Midline Pain: Pain along the spine, especially with movement, accompanied by local tenderness and a sensory level below which sensation is lost.
• Diaphragmatic Breathing: Observed when intercostal muscles are damaged but C3-5 spinal segments remain intact, allowing diaphragmatic control.
• Acute Paraplegia and Quadriplegia: Result from spinal cord damage above T1, affecting motor and sensory functions in the limbs.
• Priapism: Persistent, often painful erection due to loss of sympathetic tone, along with hypotension and bradycardia.

Transection May Be Incomplete

• Hemisection of the Cord (Brown-Séquard Syndrome):
  • Loss of ipsilateral motor function (corticospinal tract) and proprioception/vibration sense (posterior columns).
  • Contralateral loss of pain and temperature sensation (spinothalamic tract).
• Anterior Cord Syndrome:
  • Bilateral weakness and loss of pain and temperature sensation due to damage to the corticospinal and spinothalamic tracts.
  • Preservation of posterior column functions like proprioception and vibration sense.
• Central Cord Syndrome:
  • More pronounced weakness and sensory loss in the upper limbs compared to the lower limbs.
  • Often results from hyperextension injuries in individuals with pre-existing cervical spondylosis.

Investigations

• Radiological Imaging:
  • Plain Radiographs (X-Rays): Lateral, anteroposterior, and odontoid peg views of the spine. The lateral view should extend to the C7/T1 junction to assess the entire cervical spine.
  • Computed Tomography (CT) Scan: Preferred for evaluating bony injuries, fractures, and dislocations. Particularly useful for assessing C1/C2 injuries.
  • Magnetic Resonance Imaging (MRI): Superior for visualizing soft tissue injuries, including ligaments, intervertebral discs, and the spinal cord. Detects bone marrow edema, ligamentous tears, and spinal cord compression.
• Neurological Assessment:
  • Comprehensive motor and sensory evaluation to determine the extent of spinal cord involvement.
  • Assessment of reflexes, muscle tone, and presence of pathological reflexes like the Babinski sign.
• Other Diagnostic Tests:
  • Nerve Conduction Studies (NCS) and Electromyography (EMG): Evaluate the function of peripheral nerves and muscles, helping differentiate between spinal and peripheral causes of neurological deficits.
  • Blood Tests: Assess for any underlying conditions that may exacerbate spinal injuries, such as coagulopathies.

Management

The management approach depends on the severity of symptoms and degree of spinal involvement. Prompt and appropriate treatment is essential to prevent permanent neurological damage.

• Initial Stabilization (ABCs):
  • A (Airway): Ensure airway patency, especially in patients with potential head injuries or reduced consciousness.
  • B (Breathing): Provide supplemental oxygen and support ventilation if necessary.
  • C (Circulation): Manage blood pressure, control bleeding, and maintain adequate perfusion.
  • D (Disability): Assess neurological status using the Glasgow Coma Scale and perform a rapid neurological exam.
  • E (Exposure and Environment): Expose the patient as necessary to identify all injuries while preventing hypothermia.
• Spinal Immobilization:
  • Apply a hard cervical collar to stabilize the neck in cases of suspected spinal injury.
  • Use additional immobilization devices like sandbags or vacuum mattresses to prevent further movement during transport.
• Respiratory Support:
  • High cervical lesions (above C5) may impair diaphragmatic breathing, necessitating mechanical ventilation.
• Pharmacological Interventions:
  • Steroids: Administration of high-dose IV methylprednisolone is controversial and should follow local protocols. Some studies suggest limited neurological benefit.
• Surgical Interventions:
  • Decompression: Urgent neurosurgical assessment for decompression if there is evidence of spinal cord compression.
  • Stabilization: Surgical fixation to stabilize the spine in cases of unstable injuries.
  • Clot Evacuation: May be necessary if there is a significant hematoma causing cord compression.
• Supportive Care:
  • Skincare: Perform regular turning every two hours to prevent pressure ulcers.
  • Bladder Management: Use intermittent catheterization to prevent overdistension and reduce infection risk.
  • Infection Prevention: Maintain aseptic techniques during catheterization and wound care.
  • Nutrition: Ensure adequate nutritional support to aid in recovery.
• Rehabilitation:
  • Early mobilization and physical therapy to restore function and prevent complications like deep vein thrombosis.
  • Occupational therapy to assist with activities of daily living.
  • Psychological support to address emotional and cognitive challenges.
• Genetic Counseling:
  • For hereditary conditions contributing to spinal instability or degeneration.

Prognosis

Spinal injuries are often life-altering with the potential for permanent neurological deficits. The prognosis depends on the severity and location of the injury, promptness of treatment, and the extent of spinal cord involvement.

• Functional Recovery: Many patients experience some degree of neurological improvement with timely and appropriate management, especially if the spinal cord is not completely transected.
• Persistent Deficits: May include chronic pain, motor weakness, sensory loss, and autonomic dysfunction.
• Complications: Include respiratory issues, pressure ulcers, deep vein thrombosis, urinary tract infections, and psychological challenges like depression.
• Mortality: Higher in cases with high cervical or complete spinal cord injuries.
• Quality of Life: Enhanced with comprehensive rehabilitation, assistive devices, and support systems.

Prevention

• Safety Measures: Use seat belts and headrests in vehicles, wear appropriate protective gear during sports, and implement fall prevention strategies in the elderly.
• Ergonomic Practices: Maintain proper posture, especially during prolonged activities like computer work, to reduce neck and spinal strain.
• Strength Training: Strengthen neck and back muscles to provide better support for the spine.
• Health Management: Address and manage pre-existing spinal conditions like cervical spondylosis and ankylosing spondylitis to minimize injury risks.

References

• American Association of Neurological Surgeons. (2020). Spinal Cord Injury. Retrieved from AANS Spinal Cord Injury
• Tehranzadeh, J., & Lovelock, S. H. (2014). Management of Cervical Spine Injuries. Spine, 39(1), E45-E52.
• Hooper, S., Kwon, B. K., & Vopat, B. (2016). Early Management of Cervical Spine Injury in Trauma Patients. Emergency Medicine Clinics of North America, 34(4), 761-774.
• Greenwood, J. A., & Youssef, R. A. (2015). Spinal Cord Injury. In *Spinal Cord Injury Rehabilitation* (pp. 45-60). Springer.
• National Institute of Neurological Disorders and Stroke. (2021). Spinal Cord Injury Information Page. Retrieved from NINDS Spinal Cord Injury

Collection of Algorithms

• Figure 1: Canadian C-Spine Rule Algorithm for assessing cervical spine injury risk.
• Figure 2: Cervical Spine Clearance Protocol.
• Figure 3: C-Spine Trauma Assessment Flowchart.

Additional Protocols

• ABCDE Assessment: A systematic approach to trauma patient evaluation.
  • A (Airway): Ensure airway patency, especially in cases with potential cervical spine injury.
  • B (Breathing): Assess and support breathing as needed.
  • C (Circulation): Evaluate and manage circulation, controlling any hemorrhage.
  • D (Disability): Conduct a neurological assessment, including the Glasgow Coma Scale.
  • E (Exposure and Environment): Fully expose the patient to identify all injuries while preventing hypothermia.
• Throughout all stages of assessment, protect the person's cervical spine using manual in-line stabilization, especially during airway management, and avoid unnecessary movement of the spine.
• Assess for spinal injury by evaluating factors such as:
  • Presence of distracting injuries.
  • Influence of drugs or alcohol affecting cooperation.
  • Confusion or reduced consciousness levels.
  • Neck pain or tenderness.
  • Weakness or altered sensation in the extremities.
  • Priapism in unconscious or exposed males.
  • History of previous spinal issues or surgeries.

Assessment for Cervical Spine Injury

• Determine the risk category using the Canadian C-Spine Rule:
  • High Risk: Presence of any high-risk factors, such as age 65 or older, dangerous mechanisms of injury, or paraesthesia in the limbs.
  • Low Risk: Presence of low-risk factors like minor rear-end motor vehicle collisions, being ambulatory, and absence of midline cervical spine tenderness.
  • No Risk: If the patient has low-risk factors and can actively rotate their neck 45 degrees left and right.

Assessment for Thoracic or Lumbosacral Spine Injury

• Evaluate based on factors such as:
  • Age 65 or older with thoracic or lumbosacral spine pain.
  • Dangerous mechanisms like falls from heights or axial loads to the spine.
  • Pre-existing spinal pathology or osteoporosis.
  • Suspected spinal fractures in other regions.
  • Neurological symptoms like paraesthesia, weakness, or numbness.
  • Physical examination findings like abnormal neurological signs, spinal deformities, or midline tenderness.
  • Pain or abnormal neurological symptoms upon mobilization (e.g., sitting, standing, walking).
• Special consideration for children: Assess according to developmental stage and ability to communicate symptoms effectively.

When to Carry Out or Maintain Full In-Line Spinal Immobilisation

• Carry out or maintain full in-line spinal immobilisation if:
  • A high-risk factor for cervical spine injury is identified as per the Canadian C-Spine Rule.
  • A low-risk factor is present but the patient is unable to actively rotate their neck 45 degrees.
  • There is uncertainty regarding spinal injury and the potential for movement may exacerbate the condition.
• Do not carry out or maintain full in-line spinal immobilisation if:
  • The patient has low-risk factors, is pain-free, and can actively rotate their neck 45 degrees left and right.
  • There are no indications or factors suggesting a spinal injury based on the assessment criteria.

How to Carry Out Full In-Line Spinal Immobilisation

• Customize the immobilization approach based on the patient's specific circumstances, considering factors like neck size, existing deformities, and overall condition.
• In uncooperative or distressed individuals, including children, allow them to find a comfortable position while maintaining manual in-line spinal immobilization.
• For adults:
  • Fit an appropriately sized semi-rigid collar unless contraindicated (e.g., compromised airway, known spinal deformities like ankylosing spondylitis).
  • Reassess the airway after applying the collar to ensure patency.
  • Place and secure the patient on a scoop stretcher to minimize spinal movement.
  • Use head blocks and tape, preferably in a vacuum mattress, to maintain spinal alignment.
• For children:
  • Follow the same stepwise approach as for adults, ensuring comfort while maintaining spinal immobilization.

References

• NICE Guidelines: Spinal Injury Assessment and Initial Management
• American College of Surgeons. (2018). Advanced Trauma Life Support (ATLS) Student Course Manual.
• Weinstein, J. N., Tosteson, T. D., Lurie, J. D., et al. (2008). Effect of surgery vs. conservative treatment for lumbar spinal stenosis. JAMA, 300(15), 1525-1533.
• Keel, M. L., Johnston, K., Bond, R. E., & Thrasher, J. F. (1999). Evaluation of the Canadian C-Spine Rule. New England Journal of Medicine, 341(3), 198-203.
• Wright, D. W., & The Acute Spine Pain Study Group. (2001). The Canadian C-Spine Rule for Radiography in Alert and Stable Trauma Patients. Annals of Emergency Medicine, 37(5), 514-523.