Makindo Medical Notes"One small step for man, one large step for Makindo" |
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Children with a lazy eye or strabismus (deviation of the eye, usually inward) that persists beyond 3 months need an ophthalmologic referral.
Cause | Mechanism | Clinical Features |
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Congenital (Infantile) Esotropia | Maldevelopment of the brain's binocular vision mechanisms. Usually presents early in infancy. |
- Inward turning of one or both eyes.
- Presents within the first 6 months of life. - May have a family history of strabismus. - Reduced binocular vision; risk of amblyopia. |
Accommodative Esotropia | Hypermetropia (farsightedness) causes the eye to turn inward while focusing, due to excessive accommodative effort. |
- Onset usually between ages 2-4.
- Inward turning of the eye when focusing on close objects. - May improve with corrective lenses (glasses for hyperopia). - Good prognosis with early treatment. |
Intermittent Exotropia | Weakness in eye muscles or poor control over binocular coordination, causing the eye to drift outward. |
- Outward turning of the eye, particularly when tired or daydreaming.
- Can be intermittent (only at times), often worse when looking into the distance. - May close one eye in bright light. - Typically presents in childhood. |
Paralytic (Nerve Palsy) | Damage to cranial nerves (III, IV, or VI) responsible for eye movement, causing paralysis of one or more extraocular muscles. |
- Sudden onset of misalignment and diplopia (double vision).
- Depending on the affected nerve: - CN III Palsy: Eye deviated "down and out," ptosis, dilated pupil. - CN IV Palsy: Eye drifts upward, worse on downward gaze. - CN VI Palsy: Inability to abduct the eye (move outward). |
Restrictive Strabismus | Mechanical restriction of the extraocular muscles due to trauma, inflammation, or thyroid eye disease (Graves' orbitopathy). |
- Limited eye movement in the direction of the affected muscle.
- May present with proptosis in thyroid eye disease. - Diplopia, particularly in certain directions of gaze. - Eye appears misaligned in primary gaze. |
Duane Retraction Syndrome | Congenital disorder where cranial nerve VI (abducens) is underdeveloped, leading to restricted eye movement. |
- Limited abduction (outward movement) of the affected eye.
- Eye retracts into the socket when trying to look outward. - May be associated with head tilt to compensate for the limited eye movement. - Present from birth, often diagnosed in early childhood. |
Convergence Insufficiency | Inability of the eyes to converge properly while focusing on a near object, leading to outward drift of one eye. |
- Difficulty reading or focusing on near tasks.
- Eye strain, headaches, and double vision during close work. - May affect academic performance in school-aged children. - Often responds to vision therapy or convergence exercises. |
Trauma | Direct injury to the orbit or extraocular muscles, causing misalignment of the eyes. |
- Diplopia following trauma to the face or orbit.
- Restricted eye movement due to muscle entrapment or nerve damage. - Visible bruising or swelling around the eye. - Immediate referral to ophthalmology or maxillofacial surgery. |
Neurological Disorders | Conditions like multiple sclerosis, stroke, or brain tumours that affect cranial nerves or brain centers controlling eye movements. |
- Sudden or gradual onset of strabismus with other neurological symptoms (e.g., numbness, weakness, ataxia).
- May present with diplopia, nystagmus, or blurred vision. - Requires urgent neuroimaging and neurological referral. |