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Constipation = infrequent, hard or difficult stool passage, often <3 bowel motions per week or requiring straining/manual assistance.
Prevalence in older adults: up to 30% in community;>50% in institutional care.
Causes are usually multifactorial.
⚙️ Pathophysiology in Ageing
- 🧠 ↓ Autonomic function and slowed colonic transit.
- 🦴 ↓ Mobility & muscle tone.
- 🧬 Pelvic floor dysfunction & weak abdominal muscles.
- 🛏️ Institutionalisation and dependence on carers.
- 💊 Polypharmacy: anticholinergics, opioids, calcium channel blockers, iron, diuretics, TCAs.
🔎 Common Causes (Mnemonic: “DOPED”)
- Drugs – opioids, anticholinergics, calcium supplements, iron, antidepressants.
- Obstipation – bowel obstruction, cancer, strictures.
- Painful conditions – fissures, haemorrhoids, immobility.
- Endocrine/metabolic – hypothyroidism, diabetes, hypercalcaemia, hypokalaemia.
- Dehydration/diet – low fibre, low fluid intake, malnutrition.
🚨 Red Flags (need urgent investigation)
- 💔 Unintentional weight loss.
- 💉 Anaemia (iron deficiency).
- 🩸 Rectal bleeding or melaena.
- 🧠 Family history of bowel cancer.
- ⚡ New-onset constipation in >50 years.
- ⛔ Abdominal distension + vomiting (obstruction).
🧑⚕️ Assessment
- 📋 History: bowel frequency, stool type (Bristol Stool Chart), diet, mobility, drugs, pain, red flags.
- 👩⚕️ Exam: abdominal exam, PR exam (faecal loading, masses, rectal tone, prostate in men).
- 🧪 Investigations: U&E (dehydration), Ca (hypercalcaemia), TFTs, glucose. Consider colonoscopy if red flags.
🛠️ Management – Stepwise
1️⃣ General Measures
- 💧 Adequate hydration (≥1.5 L/day if safe).
- 🥗 High-fibre diet (fruits, vegetables, wholegrains).
- 🚶 Encourage mobility & exercise.
- 🪑 Regular toileting routine, optimise privacy & dignity.
- 👓 Ensure sensory aids (glasses, hearing aids) for toileting independence.
2️⃣ Medication Review
- 🔍 Stop or switch constipating drugs if possible (opioids, anticholinergics, iron, CCBs).
- 💊 Consider opioid antagonists (e.g. naloxegol) for refractory opioid-induced constipation.
3️⃣ Laxatives (NICE CG99, BGS guidance)
- 💦 Osmotic: First-line for chronic constipation (e.g. macrogol [Movicol], lactulose). Draws water into bowel.
- 🌱 Bulk-forming: (e.g. ispaghula husk/Fybogel) if adequate hydration & no obstruction.
- ⚡ Stimulant: (e.g. senna, bisacodyl) if inadequate response. Stimulates peristalsis.
- 🛑 Stool softeners: (e.g. docusate sodium) useful if hard stool.
- 💉 Suppositories/enemas: (glycerol, phosphate enema) for impaction or rapid relief.
4️⃣ Faecal Impaction Management
- Step 1: High-dose oral macrogol (up to 8 sachets/day, taper when disimpacted).
- Step 2: Add stimulant laxative (senna/bisacodyl).
- Step 3: Suppositories (glycerol, bisacodyl) or phosphate enema if refractory.
- Step 4: Manual evacuation in resistant cases (specialist care).
🛡️ Special Considerations in Elderly
- 🧠 Dementia/delirium: constipation may present as agitation or confusion.
- 🛏️ Immobility: regular bowel charts and proactive laxatives often required.
- 🧾 Polypharmacy: always review meds - opioids, anticholinergics, calcium, iron.
- ⚖️ Dignity: private toileting, avoid unnecessary catheterisation or diapers if constipation-related incontinence is reversible.
- 🏥 Care homes: bowel charts, PR exams often neglected - must be routine.
📝 OSCE / Exam Pearls
- ❓ "Elderly with acute confusion" → always consider constipation.
- 📋 Always mention hydration, mobility, fibre, medication review before laxatives.
- ⚡ For opioid-induced constipation: use stimulant ± osmotic from the outset (don’t wait for constipation to develop).
- 🚨 Never prescribe bulk-forming laxatives if bowel obstruction suspected.
- 🧠 In OSCE: demonstrate Bristol Stool Chart knowledge.
🎯 Key Takeaway
Constipation in the elderly is multifactorial, common, and high-risk.
Approach holistically: hydration + diet + mobility + medication review + appropriate laxatives.
Always look for red flags, and remember constipation can present as delirium or urinary retention in older adults. 🌟
🧑⚕️ Case Examples - Constipation in the Elderly
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Case 1 (Medication-induced): 💊
An 82-year-old woman with osteoarthritis and atrial fibrillation presents with infrequent, hard stools and straining. She is on codeine for chronic pain and verapamil for rate control. Examination is unremarkable. Diagnosis: Opioid and calcium channel blocker–induced constipation. Managed by reviewing analgesia (consider stopping codeine), introducing a stimulant laxative (senna) plus a stool softener, and encouraging hydration and mobility.
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Case 2 (Slow transit + immobility): 🪑
A 90-year-old man in a nursing home has constipation, bloating, and decreased appetite. He is largely chair-bound after a hip fracture. Abdominal exam shows mild distension but no masses. Diagnosis: Slow transit constipation due to reduced mobility and frailty. Managed with regular osmotic laxatives (lactulose or macrogol), mobilisation support with physiotherapy, and ensuring adequate dietary fibre and fluids.
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Case 3 (Secondary to obstruction): 🚨
A 77-year-old woman presents with progressive constipation, weight loss, and iron-deficiency anaemia. On exam, she has a palpable left iliac fossa mass. Colonoscopy confirms an obstructing sigmoid carcinoma. Diagnosis: Constipation secondary to colorectal cancer. Managed with surgical resection after staging and optimisation, alongside palliative laxatives for symptomatic relief.