Makindo Medical Notes"One small step for man, one large step for Makindo" |
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Related Subjects: |Ferritin |CEA |ESR |CRP |ALP |LDH |HbA1c |Alpha Fetoprotein |Anti-Hu ab |Biochemical Lab values
Acute Phase Reactant | Description | C-reactive protein (CRP) | Produced by the liver in response to inflammation. Commonly used as a marker of inflammation, infection, or tissue injury. |
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Fibrinogen | A clotting factor that is converted to fibrin during blood clot formation. Increased levels contribute to the erythrocyte sedimentation rate (ESR). |
Serum amyloid A (SAA) | A protein that increases significantly during acute inflammation. Involved in cholesterol transport and immune modulation. |
Ferritin | An iron storage protein that increases in response to inflammation. Helps sequester iron from pathogens during infection. |
Haptoglobin | Binds free haemoglobin released from red blood cells, preventing oxidative damage. Levels increase during inflammation and haemolysis. |
Alpha-1 antitrypsin | A protease inhibitor that protects tissues from enzymes of inflammatory cells. Increases during acute inflammation to counteract proteolytic damage. |
Ceruloplasmin | A copper-binding protein that plays a role in iron metabolism. Increases in response to inflammation and is involved in antioxidant defense. |
Negative Acute Phase Reactants: are proteins whose levels decrease during the acute phase response | |
Albumin | A major plasma protein involved in maintaining osmotic pressure and transporting substances. Levels decrease during inflammation as synthesis shifts toward positive acute phase reactants. |
Transferrin | An iron transport protein that decreases during inflammation. Reduction helps limit iron availability to pathogens. |
Transthyretin (Prealbumin) | A transport protein for thyroid hormones and retinol-binding protein. Levels decrease during acute inflammatory states. |