Makindo Medical Notes"One small step for man, one large step for Makindo" |
|
---|---|
Download all this content in the Apps now Android App and Apple iPhone/Pad App | |
MEDICAL DISCLAIMER: The contents are under continuing development and improvements and despite all efforts may contain errors of omission or fact. This is not to be used for the assessment, diagnosis, or management of patients. It should not be regarded as medical advice by healthcare workers or laypeople. It is for educational purposes only. Please adhere to your local protocols. Use the BNF for drug information. If you are unwell please seek urgent healthcare advice. If you do not accept this then please do not use the website. Makindo Ltd. |
This is a staging system for an appendix tumour but shows the typical form. Different tumours may follow a similar basic idea, though the details may vary.
The "T" in the TNM system, along with a letter or number (0 to 4), describes the size and location of the tumour.
Stage | Description |
---|---|
TX | The primary tumour cannot be evaluated. |
T0 | No evidence of cancer in the appendix. |
Tis | Carcinoma in situ; cancer cells are only in the inner layers lining the appendix. |
T1 | The tumour has invaded the submucosa, the next deepest layer. |
T2 | The tumour has invaded the muscularis propria. |
T3 | The tumour has grown through the muscularis propria into the subserosa or mesoappendix (connective or fatty tissue next to the appendix). |
T4 | The tumour has grown through the visceral peritoneum or invaded other nearby organs. |
T4a | The tumour has invaded the visceral peritoneum. |
T4b | The tumour has invaded other organs or structures, such as the colon or rectum. |
The "N" in the TNM system stands for lymph nodes.
Stage | Description |
---|---|
NX | The regional lymph nodes cannot be evaluated. |
N0 | No regional lymph node metastasis. |
N1 | Cancer has spread to 1 to 3 regional lymph nodes. |
N2 | Cancer has spread to 4 or more regional lymph nodes. |
The "M" in the TNM system describes cancer spread to other parts of the body, such as the liver or lungs.
Stage | Description |
---|---|
M0 | No distant metastasis. |
M1 | Distant metastasis present. |
M1a | Intraperitoneal acellular mucin present. |
M1b | Metastasis within the peritoneum beyond M1a. |
M1c | Metastasis beyond the peritoneum. |
Histological grade (G) indicates the differentiation of the tumour cells.
Grade | Description |
---|---|
GX | Tumour grade cannot be identified. |
G1 | Well-differentiated tumour cells. |
G2 | Moderately differentiated tumour cells. |
G3 | Poorly differentiated tumour cells. |
G4 | Undifferentiated tumour cells. |